Information for
Clinicians

Clinical caregivers are central to advances for patients with kidney diseases. As key stakeholders, clinicians can increase awareness and participation in the KPMP. Readily available study information and videos of patient experiences are provided to bring the KPMP to a broad clinical community.

Study criteria

KPMP enrolls participants with CKD or AKI. CKD participants may have diabetic kidney disease or hypertensive kidney disease. Inclusion criteria for each study cohort and the general exclusion critieria is listed below.

Inclusion

Diabetic Kidney Disease (Type 1 or 2)

  • eGFR 30-59mL/min/1.73m2 OR
  • eGFR ≥ 60 with UPCR >150mg/g or UACR >30 mg/g

Diabetic Kidney Disease Resilient Individuals Inclusion Criteria

  • Type 1 diabetes for over 25 years
  • Estimated glomerular filtration rate greater than or equal to 60 mL/min/1.73m2
  • Urine albumin excretion less than 30 mg/d (or mg/g creatinine)

Hypertensive Kidney Disease

  • eGFR30-59/min/1.73m2 with UPCR or UACR
  • eGFR ≥ 60 with UACR 30-2000mg/g or UPCR 150-2000 mg/g

Acute Kidney Injury

  • Baseline eGFR >45mL/min/1.73m2
  • Elevated serum creatinine ≥1.5x baseline, AND one of the following:
  • Further serum creatinine increase of 0.3 mg/dL
  • Positive kidney injury urine biomarkers (NGAL, Kim1, TIMP2 x IGFBP7)
  • Urine microscopy suggestive of ATN

Healthy Reference Groups

  • Undergoing percutaneous nephrolithotomy for treatment of symptomatic renal stones without evidence of pyelonephritis
  • Participating in a living donor kidney transplantation as the donor

Exclusion

  • Age (<18 years)
  • Glomerular disease, Kidney transplant, Pregnancy
  • Increased biopsy complication risk (Chronic anticoagulation, Platelets <100, INR>1.4, Hb <8.5, aspirin intake within 7 days of biopsy, Hypotension or BP that cannot be controlled to >160/100mmHg at time of biopsy).

Study procedures

KPMP participants are asked to do the following:

  • Have a biopsy of their kidney for research purposes.
  • Give blood, urine and stool.
  • Provide our study team with information about them.
  • Talk to our study team 2-3 times a year for up to 10 years.

Clinician Resources

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Clinician Primer

Information about the study for clinicians

publications icon

Brochure

Informational brochure for patients

protocols icon

FAQ

Frequently asked questions for patients

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Presentation

KPMP Overview Powerpoint presentation

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AKI Fact sheet

Talking points brochure for clinicians with AKI patients

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CKD fact sheet

Talking points brochure for clinicians with CKD patients

Site Contacts

If you have a patient who would be a good candidate for KPMP, you can reach out to your nearest study center for more information.

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Contact information
Link to current site

Boston University

Boston
MA
Boston, MA
FOCUS:
CKD
Investigator(s):
Phone:
EMAIL:
KPMPrc-bmc@uw.edu
Link to current site

Cleveland Clinic

Cleveland
OH
Cleveland, OH
FOCUS:
CKD
Investigator(s):
Phone:
(216) 444-7954
EMAIL:
kpmprc-ccf@uw.edu
Link to current site

Johns Hopkins

Baltimore
MD
Baltimore, MD
FOCUS:
AKI
Investigator(s):
Phone:
(410) 502-3852
EMAIL:
kpmprc-jhmi@uw.edu
Link to current site

Joslin Diabetes Center/Beth Israel Deaconess Medical Center

Boston
MA
Boston, MA
FOCUS:
CKD
Investigator(s):
Phone:
(617) 309-4130
EMAIL:
kpmprc-joslin@uw.edu
Link to current site

Mount Sinai

New York
NY
New York, NY
FOCUS:
AKI and CKD
Investigator(s):
Phone:
EMAIL:
KPMPrc-mssm@uw.edu
Link to current site

University of Arizona

Tucson
AZ
Tucson, AZ
FOCUS:
AKI and CKD
Investigator(s):
Link to current site

University of Illinois, Chicago

Chicago
IL
Chicago, IL
FOCUS:
CKD
Investigator(s):
Phone:
EMAIL:
KPMPrc-uic@uw.edu
Link to current site

University of Minnesota

Minneapolis
MN
Minneapolis, MN
FOCUS:
CKD
Investigator(s):
Phone:
EMAIL:
KPMPrc-umn@uw.edu
Link to current site

University of North Carolina

Chapel Hill
NC
Chapel Hill, NC
FOCUS:
AKI and CKD
Investigator(s):
Phone:
EMAIL:
KPMPrc-unc@uw.edu
Link to current site

University of Texas Southwestern, Dallas

Dallas
TX
Dallas, TX
FOCUS:
CKD
Investigator(s):
Phone:
(214) 615-8291
EMAIL:
kpmprc-utsw@uw.edu
Link to current site

Yale University

New Haven
CT
New Haven, CT
FOCUS:
AKI
Investigator(s):
Phone:
‍‍(203) 737-1787
EMAIL:
kpmprc-yale@uw.edu
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Get involved

We value the input of clinicians as we work to grow our study. The KPMP Community Engagement Committee is made up of KPMP site members,patient partners, ethicists and community clinicians. The group meets monthly to receive updates on the study and discuss issues of interest.

If you are interested in participating in the KPMP Community Engagement Committee, join our mailing list:

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