Opportunity Pool Funding

Recent advances in multi-scale interrogation of human tissue and single cells have set the stage for precision medicine to be applied to kidney disease. The objectives of the Kidney Precision Medicine Project are to ethically and safely obtain and evaluate human kidney biopsies from participants with Acute Kidney Injury (AKI) or Chronic Kidney Disease (CKD), create a kidney tissue atlas, define disease subgroups, and identify critical cells, pathways and targets for novel therapies. Learn more about the KPMP protocols and processes.

The Opportunity Pool process

The Opportunity Pool is managed by the Central Hub and administered by Mount Sinai. Ian de Boer, MD (University of Washington) and Laura Mariani, MD (University of Michigan) serve as Opportunity Pool Co-Directors. The Opportunity Pool is responsible for the following:

  • Facilitating communication with applicants
  • Recruitment of external peer reviewers
  • Correspondence with reviewers
  • Collection of the critiques
  • Disbursement and accounting of funds

The Central Hub closely supervises the external peer review process and serves as a resource for potential applicants.

KPMP Travel Grants

The Kidney Precision Medicine Project supports professional development opportunities for early-career investigators. One such opportunity allows investigators to attend KPMP Steering Committee meetings and present posters on their research as relevant to KPMP.

Early-stage investigators who attended past meetings have learned about KPMP protocols in development, scientific technologies to be applied to the interrogation of kidney biopsy tissue, the role of patient and community engagement in KPMP, and how data management and visualization tools will be applied to the creation of the Kidney Tissue Atlas.

In addition to the opportunity to present during the meeting’s poster session, early-stage investigators are awarded a travel stipend. Interested candidates must submit an NIH biosketch and an abstract of their research. Abstracts will undergo a peer-review process for scoring.

Current Opportunities

Early Career Investigator Travel Grants for March 2025 KPMP Meeting

ID Number:

RFA-KPMP-OP-24-001

Earliest submission date:

Oct 21, 2024

Application due date:

Jan 09, 2025 by 5 p.m. Eastern

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Past Funding opportunities & Awardees

RFA-KPMP-OP-23-003: KPMP Glue Grant

ID Number:

RFA-KPMP-OP-23-003

Earliest submission date:

Apr 22, 2024

Application due date:

Jun 14, 2024 by 5 p.m. Eastern

Awardees:

Ensemble framework for predicting regulatory variants in rare kidney cell types.

Dongwon Lee Boston Children's Hospital

Visual Analytics for Exploration and Hypothesis Generation Using Highly Multiplexed Spatial Data of Tissues and Tumors

Sandro Santagata Harvard Medical School

3D Image-Omics Integration for Spatial Transcriptomics in High Definition

Yuankai Huo Vanderbilt University

Diabetes StudY in Nephropathy And other Microvascular cOmplications (DYNAMO)

Thomas Coffman Duke-NUS Medical School

RFP-KPMP-OP-21-003 : Whole Genome Sequencing (CLIA)

ID Number:

RFP-KPMP-OP-21-003

Earliest submission date:

Mar 1, 2022

Application due date:

Apr 01, 2022 by 5 p.m. Eastern

Awardees:

Columbia University

RFP-KPMP-OP-21-002: Whole Genome Sequencing on KPMP Participants

ID Number:

RFP-KPMP-OP-21-002

Earliest submission date:

Oct 15, 2021

Application due date:

Nov 30, 2021 by 5 p.m. Eastern

Awardees:

No awards were issued.

RFP-KPMP-OP-21-001: KPMP Biomarker Measurements

ID Number:

RFP-KPMP-OP-21-001

Earliest submission date:

Aug 16, 2021

Application due date:

Oct 25, 2021 by 5 p.m. Eastern

Awardees:

Hamid Rabb (Johns Hopkins)
Sequencing KPMP AKI stool microbiome samples

Kalani Raphael (OHSU) & John Asplin (Litholink)
Enhancing the phenotype of KPMP participants with measurements of urinary electrolytes and acid-base parameters

Metabolon Inc
Metabolite profiling of KPMP participants

Somalogic
Somascan 7,000 proteomics analysis of EDTA plasma and urine samples from the KPMP cohort

Wassim Obeid & Chirag Parikh (Johns Hopkins)
Measurement of blood and urinary biomarkers to enhance the KPMP tissue atlas

RFI-KPMP-OP-21-001: Request for Information: KPMP Biomarker measurement

ID Number:

RFI-KPMP-OP-21-001

Earliest submission date:

May 12, 2021

Application due date:

Jun 11, 2021 by 5 p.m. Eastern

Awardees:

RFA-KPMP-OP-20-005-COVID: COVID-19 research at KPMP sites

ID Number:

RFA-KPMP-OP-20-005-COVID

Earliest submission date:

Jun 26, 2020

Application due date:

Jul 20, 2020 by 5 p.m. Eastern

Awardees:

Miguel Vazquez & Bob Toto (UT Southwestern)
Kidney Precision Medicine Project, COVID-19 research at KPMP sites

Stewart Lecker & Sylvia Rosas (Beth Israel Deaconess Medical Center)
Acute Kidney Injury and COVID-19: KPMP substudy

Steve Menez & Chirag Parikh (Johns Hopkins University)
Kidney Injury in Patients with COVID-19: A Sub-study of the Kidney Precision Medicine Project

Perry Wilson & Dennis Moledina (Yale University)
Phenotyping AKI in COVID-19 Cohort (PACC) Study

RFA-KPMP-OP-20-004: Perform KPMP research biopsies on existing kidney disease cohorts

ID Number:

RFA-KPMP-OP-20-004

Earliest submission date:

Mar 1, 2020

Application due date:

May 01, 2020 by 5 p.m. Eastern

Awardees:

Jonathan Taliercio, DO (Cleveland Clinic)
Cleveland CRIC KPMP

RFA-KPMP-OP-20-002: Develop and test novel tissue interrogation technologies

ID Number:

RFA-KPMP-OP-20-002

Earliest submission date:

Mar 1, 2020

Application due date:

May 01, 2020 by 5 p.m. Eastern

Awardees:

Lloyd Cantley, MD (Yale University)
Spatially preserved cell state phenotyping using Imaging Mass Cytometry-Kidney-MAPPS

Anna Greka, MD, PhD & Jamie Marshall, PhD (Broad Institute)
Slide-seq: spatial transcriptomic technology for tissue interrogation

Michael Rauchman, MDCM (Washington University St. Louis)
Chromatin Profiling of Nephrectomy and Kidney Biopsy Tissues

RFA-KPMP-OP-20-005: Glue Grant May 2020

ID Number:

RFA-KPMP-OP-20-005

Earliest submission date:

Mar 1, 2020

Application due date:

May 01, 2020 by 5 p.m. Eastern

Awardees:

Ari Pollack, MD (Seattle Children’s/University of Washington)
Designing a Visual Decision Aid for Shared Decision Making after Renal Biopsy

RFA-KPMP-OP-20-003: Test tools or methods to enhance KPMP clinical phenotyping

ID Number:

RFA-KPMP-OP-20-003

Earliest submission date:

Mar 1, 2020

Application due date:

May 01, 2020 by 5 p.m. Eastern

Awardees:

Sus Waikar, MD, MPH (Boston University)
Anand Srivastava, MD, MPH (Northwestern University)
Pottumarthi Prasad, PhD (Northshore)
ADVANCING MULTIPARAMETRIC KIDNEY FUNCTIONAL MRI TO PHENOTYPE INDIVIDUALS WITH CKD

Sus Waikar, MD, MPH (Boston University)
Petter Bjornstad, PhD (University of Colorado)
Kidney Physiology Phenotyping in the Kidney Precision Medicine Project

Ian de Boer, MD (University of Washington)
Sylvia Rosas, MD (Joslin Diabetes Center)
Advanced retinal phenotyping to identify mechanistic pathways in chronic kidney disease

RFA-KPMP-OP-19-005: Glue Grant October 2019

ID Number:

RFA-KPMP-OP-19-005

Earliest submission date:

Sep 1, 2019

Application due date:

Oct 01, 2019 by 5 p.m. Eastern

Awardees:

Jeffrey Spraggins, PhD & Richard Caprioli, PhD (Vanderbilt University)
Integrating the VU Biomolecular Multimodal Imaging Center of HuBMAP with the Kidney Precision Medicine Project

Katy Borner, PhD (Indiana University)
Harmonizing KPMP/HuBMAP Data: Developing Common Coordinate Framework UI

Anant Madabhushi, PhD (Case Western Reserve)
HistoTools: A suite of digital pathology tools for quality control, annotation, and dataset identification

Pinaki Sarder, PhD (University of Buffalo)
A Computational Renal Pathology Suite for KPMP

RFA-KPMP-OP-19-003: Healthy Reference Tissue

ID Number:

RFA-KPMP-OP-19-003

Earliest submission date:

May 28, 2019

Application due date:

Jun 28, 2019 by 5 p.m. Eastern

Awardees:

Minnie Sarwal, MD (UCSF)
Building Health Kidney Tissue Repository for KPMP

James Williams, PhD (Indiana University)
Healthy Reference Tissue for KPMP

E. Steven Woodle, MD (University of Cincinnati)
Kidney Precision Medicines Project Healthy Living Kidney Donor Tissue Repository

Kalani Raphael, MD (OHSU) & John Asplin, MD (Litholink)
Enhancing the phenotype of KPMP participants with measurements of urinary electrolytes and acid-base parameters

Metabolon Inc
Metabolite profiling of KPMP participants

Somalogic
Somascan 7,000 proteomics analysis of EDTA plasma and urine samples from the KPMP cohort

Wassim Obeid, PhD & Chirag Parikh, MD (Johns Hopkins)
Measurement of blood and urinary biomarkers to enhance the KPMP tissue atlas

RFA-KPMP-OP-19-005: Glue Grant June 2019

ID Number:

RFA-KPMP-OP-19-005

Earliest submission date:

May 28, 2019

Application due date:

Jun 28, 2019 by 5 p.m. Eastern

Awardees:

Petter Bjornstad, MD (University of Colorado)
Tissue based integrative biology of early diabetic kidney disease in youth-onset type 2 diabetes

RFA-KPMP-OP-19-004: Biomimetic Phantoms

ID Number:

RFA-KPMP-OP-19-004

Earliest submission date:

May 28, 2019

Application due date:

Jun 28, 2019 by 5 p.m. Eastern

Awardees:

Steve Bogen, MD, PhD (Boston Cell Standards, LLC)
Analytic Calibrators and Controls Core Resource for Protein Biomarker Testing

Hongping Ye, PhD (UTHSA)
Human Kidney Mimetic Tissue Using Endogenous Lips and Metabolites as Secondary Standards

Travel grants

RFA-KPMP-OP-23-004: Early Career Investigator Travel Grants for September 2024 KPMP Meeting

ID Number:

RFA-KPMP-OP-23-004

Earliest submission date:

Apr 18, 2024

Application due date:

Jul 12, 2024 by 5 p.m. Eastern

Awardees:

Ramya Narasimhan Boston University

Nanditha Anandakrishnan Icahn School of Medicine at Mount Sinai

Sok Cin Tye Joslin Diabetes Center

Amin Abedini University of Maryland Medical Center Midtown Campus

Thai Huy Pham Vanderbilt University

Jovan Tanevski Heidelberg University

Jonathan Nelson University of Southern California

Sayat Mimar University of Florida

Azuma Nanamatsu Indiana University

Katerina Trachtova Jain Lab, Washington University in St. Louis, MO

Leila Hejazi SygnaMap

Danielle Janosevic Indiana University

RFA-KPMP-OP-23-001: Early Career Investigator Travel Grants for February 2024 KPMP Meeting

ID Number:

RFA-KPMP-OP-23-001

Earliest submission date:

Nov 17, 2023

Application due date:

Dec 21, 2023 by 5 p.m. Eastern

Awardees:

Fan Fan,  Emory University, Atlanta    

Chao Zhang,  Boston University School of Medicine    

Huu Hien Huynh,  University of Washington  

Insa Schmidt, Boston University

Pei Su,  Northwestern University    

Allison Esselman,  Vanderbilt University    

Jin Zhou,  Duke University    

Marina de Cos Gomez, Icahn School of Medicine at Mount Sinai    

Ricardo Melo Ferreira,  Indiana University    

Abdulsalam Soofi,  University of Michigan    

Leah Guthrie,  University of California, Berkeley    

Yuankai Huo,  Vanderbilt University    

Xiao Sun,  University of Illinois Chicago  

Debora L. Gisch,  Indiana University    

Christoph Zechner,  UT Southwestern

RFA-KPMP-OP-21-004: Travel Grant for Junior Atlas Builders Meeting

ID Number:

RFA-KPMP-OP-21-004

Earliest submission date:

Jun 21, 2022

Application due date:

Jul 28, 2022 by 5 p.m. Eastern

Awardees:

RFA-KPMP-OP-20-001: March/September 2020 Meeting

ID Number:

RFA-KPMP-OP-20-001

Earliest submission date:

Jan 14, 2020

Application due date:

Feb 04, 2020 by 5 p.m. Eastern

Awardees:

Seth Winfree (Indiana University)
Sean Eddy (University of Michigan)
Kasra Rezaei (University of Washington)
Abhijit Naik (University of Michigan)
Christine Limonte (University of Washington)
Hyun Jun Jung (Johns Hopkins University)
Insa Schmidt (Harvard University)
Angela Sabo (Indiana University)
Tianyi Zhou (Northeastern University)
Wenqing Yin (Boston University)
Ari Pollack (University of Washington)

RFA-KPMP-OP-19-002: September 2019 Meeting

ID Number:

RFA-KPMP-OP-19-002

Earliest submission date:

Jun 19, 2019

Application due date:

Jul 19, 2019 by 5 p.m. Eastern

Awardees:

Daria Barwinska*(4) (Indiana University)
Pavan Bhatraju*(1) (University of Washington)
Yijiang Chen (Case Western Reserve University)
Scott Kennedy (University of Washington)
Jessica Lukowski (Pacific Northwest National Laboratory)
Anna Mathew (University of Michigan)
Abhijit Naik (University of Michigan)
Annapurna Pamreddy (University of Texas Health Science Center, San Antonio)
Colin Reily (University of Alabama at Birmingham)
Pinaki Sarder (University at Buffalo)
Insa Schmidt (Boston University Medical Center, Renal Section)
Yanbao Yu (J. Craig Venter Institute)
Dong Zhou (University of Pittsburgh School of Medicine)

*(n) = previous awardee & number of times awarded

RFA-KPMP-OP-19-001: April 2019 Meeting

ID Number:

RFA-KPMP-OP-19-001

Earliest submission date:

Feb 1, 2019

Application due date:

Mar 01, 2019 by 5 p.m. Eastern

Awardees:

Barwinska, Daria (Indiana University)
Charu, Vivek (Stanford)
Gonzalez-Vicente, Agustin (Cleveland Clinic)
Hinson, Jeremiah (John’s Hopkins University)
Jayapandian, Cathe)rine (Center for Computational Imaging and Personalized Diagnostics (CCIPD))
Kolachalama, Vijaya (Boston University)
Spraggins, Jeffrey (Vanderbilt University)
Sreelatha, Anju (UT Southwestern)
Van de Plas, Raf (Vanderbilt University)
Velickovic, Dusan (Pacific Northwest National Laboratory)
Walsh, Michael (University of Illinois at Chicago)
Zhang, Guanshi (UT Health San Antonio)

RFA-KPMP-OP-18-004: January 2019 Meeting

ID Number:

RFA-KPMP-OP-18-004

Earliest submission date:

Oct 19, 2018

Application due date:

Nov 19, 2018 by 5 p.m. Eastern

Awardees:

Lindstrom, Nils (USC)
Avigan, Zach (Yale)
Zhang, Guanshi (UTHSA)
Barwinska, Daria (Indiana University)
Gonzalez-Vicente, Agustin (Cleveland Clinic)
Rashmi, Priyanka (UCSF)
Schoreder, Andrew (UCSF)
Srivastava, Anand (Northwestern University)
Schaub, Jen (University of Michigan)
Amodu, Afolarin (Brigham Women & Children)
Gregg, Lucile (UT Southwestern)
Zhang, Yu (Brigham Women & Children)
Cobb, Jason (Emory)
Sohaney, Ryann (University of Michigan)
Ugwuowo, Ugochukwu (Yale)

RFA-KPMP-OP-18-003: September 2018 Meeting

ID Number:

RFA-KPMP-OP-18-003

Earliest submission date:

Jun 27, 2018

Application due date:

Jul 27, 2018 by 5 p.m. Eastern

Awardees:

Zhang, Guanshi (UTHSA)
Akilesh, Shreeram (University of Washington)
Lee, Kim (Mount Sinai)
Moledina, Dennis (Yale)
Bhargava, Rhea (Beth Israel Deaconess Medical Center)
Wilson, Parker (Washington University St. Louis)
Meliambro, Kristin (Mount Sinai)
Barwinska, Daria (Indiana University)
Palsson, Ragnar (Brigham Women & Children)
Schroeder, Andrew (UCSF)
Ferre, Silvia (UT Southwestern)
Hayden, Robert (Harvard University)
Kliegel, Judith (Yale)
Mansour, Sherry (Yale)
Velickovic, Dusan (Pacific Northwest National Lab)

RFA-KPMP-OP-18-002: July 2018 Ontology Workshop

ID Number:

RFA-KPMP-OP-18-002

Earliest submission date:

May 27, 2018

Application due date:

Jun 27, 2018 by 5 p.m. Eastern

Awardees:

Palsson, Ragnar (Brigham/Harvard)
Bhargava, Rhea (BIDMC)
Almaani, Salem (Ohio State University Wexner Medical Center)
Nguyen, Jane Kim (Cleveland Clinic)

RFA-KPMP-OP-18-001: May 2018 Meeting

ID Number:

RFA-KPMP-OP-18-001

Earliest submission date:

Feb 28, 2018

Application due date:

Mar 31, 2018 by 5 p.m. Eastern

Awardees:

Hoover, Paul (Broad Institute/UMichigan)
Poyan-Mehr, Ali (Harvard)
Barwinska, Daria (Indiana University)
Winfree, Seth (Indiana University)
Lee, Kyung (Kim) (Mount Sinai)
Dieter, Brad (Providence Medical Research Center)
Zhang, Guanshi (University of Texas Health San Antonio)
Akilesh, Shreeram (University of Washington)
Bhatraju, Pavan (University of Washington)
Sweetwyne, Mariya (University of Washington)
Singh, Nikhil (Yale)

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