Kidney Precision Medicine Project

Changing the way we understand and treat kidney disease. Together.

The Kidney Precision Medicine Project (KPMP) is an ambitious, multi-year project funded by the NIDDK  with the purpose of understanding and finding new ways to treat chronic kidney disease (CKD) and acute kidney injury (AKI).

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Who we are

The KPMP is made up of four distinct, but highly interactive, activity groups:

Recruitment Sites

The recruitment sites are responsible for recruiting participants with AKI or CKD into the longitudinal study and performing the kidney biopsy.

Tissue Interrogation Sites

The tissue interrogation sites are responsible for developing and using innovative technologies to analyze the biopsy tissue.

Central Hub

The central hub is responsible for aggregating, analyzing, and visualizing the generated data and providing scientific, infrastructure, and administrative support for the KPMP consortium.

Opportunity pool awardees

We form partnerships with our Opportunity Pool awardees to collaborate with the broader research community and so  fully achieve the objectives of this project.  

Building the Kidney Tissue Atlas with our Research

Our researchers will use the kidney biopsies to make multiple maps of the kidney (called the Kidney Tissue Atlas). These maps will show important cells, regions, and disease pathways that lead to chronic kidney disease (CKD) and acute kidney injury (AKI).

The research will help answer important questions for people with kidney disease, such as:

  • What type of kidney disease do I have?
  • What will happen to me?
  • What can I do about it?

Ultimately, KPMP research hopes to find new markers and treatment targets that make personalized, effective, and safe treatments possible for kidney diseases.

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