The Kidney Precision Medicine Project (KPMP) is an ambitious, multi-year project funded by the NIDDK with the purpose of understanding and finding new ways to treat chronic kidney disease (CKD) and acute kidney injury (AKI).
The KPMP is made up of four distinct, but highly interactive, activity groups:
The recruitment sites are responsible for recruiting participants with AKI or CKD into the longitudinal study and performing the kidney biopsy.
The tissue interrogation sites are responsible for developing and using innovative technologies to analyze the biopsy tissue.
The central hub is responsible for aggregating, analyzing, and visualizing the generated data and providing scientific, infrastructure, and administrative support for the KPMP consortium.
We form partnerships with our Opportunity Pool awardees to collaborate with the broader research community and so fully achieve the objectives of this project.
Our researchers will use the kidney biopsies to make multiple maps of the kidney (called the Kidney Tissue Atlas). These maps will show important cells, regions, and disease pathways that lead to chronic kidney disease (CKD) and acute kidney injury (AKI).
The research will help answer important questions for people with kidney disease, such as:
Ultimately, KPMP research hopes to find new markers and treatment targets that make personalized, effective, and safe treatments possible for kidney diseases.
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